the key intermediate of doripenem CAS NO.491878-06-9

CAS NO: 491878-06-9

Molecular Formula: C20H28N4O9S2

Molecular Weight: 532.59

Melting Point: 124-132 ºC

H bond acceptors: 13

H bond donors: 2

Freely Rotating Bonds: 11

Index of Refraction: 1.616

Molar Refractivity: 127.58 cm3

Molar Volume: 365 cm3

Surface Tension: 69.7 dyne/cm

Density: 1.45 g/cm3

Flash Point: 369.2 °C

Enthalpy of Vaporization: 100.7 kJ/mol

Boiling Point: 686.8 °C at 760 mmHg

Vapour Pressure: 1.03E-18 mmHg at 25°C

 

Doripenem side-chain Specification

  Doripenem side-chain , with CAS number of 491878-06-9, can be called Acs-pnz-pyrrolidyl-(boc)-nso2nh2 ; Doripenem Side-Chain ; 4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate .

 

Honghui Pharmaceutical Technology Co., Ltd. is located at the foot of Huangshan Mountain, the world natural heritage. It is located in the hometown of Huishang and the famous historical and cultural city of China. It is a high-tech enterprise in Anhui Province with convenient transportation. It is adjacent to Huihang Expressway, Handan Railway and Huangshan Airport.

The company mainly produces cephalosporin and other series of intermediates, the products are sold throughout the country and exported to Japan, South Korea, India and other countries.

The company pays attention to technological progress, scientific management, society-oriented, and employers. Now it has brought together various high- and medium-level professional and management talents. They have developed their intelligence and talents for the development of enterprises in research, development, production, quality and management. The company has strong technical strength and strict quality management system; adhere to the perfect combination of honesty, credibility and quality.